I will describe aspects of contemporary physics with controlled beams and samples of positrons and antiprotons. Included will be the recent observation of cold antihydrogen, with emphasis on the results of the ATHENA collaboration. I will discuss how antihydrogen is formed when antiprotons interact with a cold, trapped positron plasma, and what can be gleaned from studies of the resulting interaction dynamics, studies at different positron temperatures and by observing the spatial distribution of the emitted anti-atoms. I will describe some possible avenues for future studies with antihydrogen, including the programme of the new ALPHA collaboration.
Over the years the positronium atom has been a great workhorse for fundamental physics. New sources of low energy positrons, including their manipulation in vacuum, will facilitate a new generation of experiments. I will provide a brief summary of activities and opportunities in this area.