First proposed in 1959 by S. L. Glashow, the resonant creation of a W− boson from the interaction of an anti-electron neutrino with an electron has never been experimentally observed. In the electron rest-frame the required neutrino energy, Eν ≈ 6.3 PeV, is orders of magnitude greater than the energies of neutrinos created in Earth-based accelerators. As such, efforts at observing the interaction have focused on large-scale high-energy neutrino observatories designed to detect neutrino interactions in a natural medium, such as the cubic kilometer of Antarctic ice instrumented by the IceCube collaboration. In the talk I will report the first Glashow resonance candidate event from IceCube and the implications for the field in the future.