Présidents de session
Mini-colloques: MC14 Sources de photons sur accélérateurs pour l'étude des biomolécules en phase gazeuse: 1
- Debora Scuderi (Institut de Chimie Physique, CNRS-Université Paris Saclay)
Mini-colloques: MC14 Sources de photons sur accélérateurs pour l'étude des biomolécules en phase gazeuse: 2
- Debora Scuderi (Institut de Chimie Physique, CNRS-Université Paris Saclay)
Photoemission and state-selected fragmentation of “aromatic cyclo-dipeptides” in the gas-phase
Linear (ℓ-) and cyclo (c-) dipeptides built by linking two aminoacids via one/two peptide bonds, are the simplest peptides present in nature. They are the object of widespread interest since the 50s of the previous century due to their central role in several areas such as development of...
DNA/RNA bases and amino acids are building blocks of life. The spectroscopy and stability of their ionic forms are relevant to their survival rate under interstellar conditions, and to the field of radiation damage, where ionizing radiation can lead to DNA/RNA strand breaking and production of hazardous by-products through processes involving nucleobases.
Several experimental works at BESSY...
Phthalocyanine are synthetic molecules closely related to the natural porphyrines. Thanks to their rich photophysics and photochemistry, they show promising potential in a wealth of applications, including biology or medicine. We are particularly interested in transition-metal containing molecules and, more precisely, to the interaction between 3d orbitals of the metal and its surrounding N 2p...
Photoelectron circular dichroism (PECD) — the forward-backward asymmetry in photoemission from chiral molecules photoionized by circularly polarized light — is an exquisitely sensitive experimental probe, capable of determining enantiomeric excess and electronic and molecular structures in chiral samples. Although the use of PECD to study chiral biomolecules under physiologically relevant...
Structural changes at the molecular level, occurring at the onset of condensation, can be probed by angle-resolved valence photoelectron spectroscopy, which is inherently sensitive to the electronic structure. For larger condensed systems like aerosol particles, the observation of intrinsic angular anisotropies in photoemission (β parameters) is challenging due to the strong reduction of their...
Mass spectrometry (MS) is one of the primary analytical methods in the characterization of complex mixtures, samples that contain thousands of molecular constituents in concentrations that vary by many orders of magnitude. Both sensitivity and resolving power of MS are unparalleled by other analytical methods. However, determination of molecular structures on the basis of MS data is...
Gas phase spectroscopy provides unique advantages by allowing access to intrinsic properties of matter in the absence of solvents, making it an excellent means to test theoretical methods. However, this approach requires placing the sample in the gas phase, which can be challenging for large or fragile species such as biomolecules. Modern ionization techniques, such as electrospray ionization...
Proton transfer is a fundamental charge transfer process in Chemistry, and it is particularly important for biological molecules, since they usually contain basic groups. Therefore, in order to study charge dynamics in isolated biomolecules, it is crucial to determine the initial location of protons. Although it is now well established that protonation occurs primarily at nitrogen atoms of the...
FLASH at DESY in Hamburg has a unique FEL scheme, which includes XUV and THz undulators, providing soft X-Ray and intense tunable THz pulses at a high repetition rate simultaneously with low jitter [1]. The combination of XUV and THz pulses at FLASH enables time-resolved pump-probe experiments to study structural and electron dynamics of molecules[2,3], coherent control of magnetization...
beta-CycloDextrin (b-CD) is a macrocyclic oligosaccharide composed of seven D-glucopyranoside units linked in alpha-(1,4) bonds. b-CD has a truncated cone tri-dimensional structure. Its central cavity is hydrophobic, allowing low-polarity molecules to be encapsulated partially or entirely by host-guest interaction, meanwhile the external part is hydrophilic because of the presence of 21...
